Material Safety Data Sheet: 4-Vinylphenol

Identification

Product Name: 4-Vinylphenol
Chemical Formula: C8H8O
CAS Number: 2628-17-3
SYNONYMS: p-Vinylphenol, para-Vinylphenol
Recommended Use: Laboratory chemicals, research and development
Manufacturer: Major chemical supply firms
Contact Information: Emergency number available on container, consult local distributor

Hazard Identification

Hazard Classification: Flammable liquid, skin irritant, eye irritant
GHS Label Elements: Signal Word: Danger, Flammable pictogram, Exclamation mark
Hazard Statements: May cause skin and eye irritation, causes serious eye damage, may cause respiratory irritation, suspected of damaging fertility
Precautionary Statements: Keep away from heat and open flames, wear protective gloves, avoid breathing dust or vapor, wash hands thoroughly after handling
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Potential Health Effects: Acute toxicity via skin or eyes, symptoms include headache, nausea, dizziness, redness, burning sensation

Composition / Information on Ingredients

Chemical Name: 4-Vinylphenol
CAS No.: 2628-17-3
Concentration: 100% (pure material)
Impurities: Small amounts of related phenolic compounds may occur as by-products, check batch QC for details
Stabilizers: Inhibitors might sometimes be present to avoid premature polymerization

First Aid Measures

Inhalation: Move victim to fresh air immediately. Seek medical attention if symptoms persist or worsen such as difficulty breathing or chest pain.
Skin Contact: Remove contaminated clothing and rinse skin with plenty of water and mild soap for at least 15 minutes. If irritation develops or persists, seek medical advice.
Eye Contact: Rinse thoroughly with running water for several minutes, holding eyelids apart. Continue irrigation for at least 15 minutes. Remove contact lenses if present and easy to do so. Seek medical attention without delay.
Ingestion: Rinse mouth, do not induce vomiting. Seek immediate medical assistance. Provide symptom-relief.
Most Important Symptoms: Irritation, redness, burning of skin and eyes, possible dizziness or headache on inhalation.

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, foam, water spray (avoid solid water streams directly on burning liquid)
Unsuitable Media: Direct water stream increases risk of spatter or spread
Special Hazards: Vapors may form explosive mixtures with air, combustion products may include toxic phenolic fumes and carbon oxides
Special Protective Equipment: Full protective gear and self-contained breathing apparatus for firefighters
Firefighting Advice: Evacuate area, cool containers exposed to heat with water in a controlled manner, prevent run-off from entering drains

Accidental Release Measures

Personal Precautions: Eliminate ignition sources, ventilate area, avoid breathing vapor, wear suitable protective clothing and gloves
Environmental Precautions: Prevent further leakage or spillage, keep away from drains, surface water, or ground water
Cleanup Methods: Absorb spills with inert absorbent (sand, earth), collect into labeled containers for disposal, use spark-proof tools and explosion-proof equipment
Decontamination: Wash spill area with water after material is removed, ventilate the space

Handling and Storage

Precautions for Safe Handling: Handle in a well-ventilated area, avoid inhaling vapor or dust, do not eat, drink, or smoke while working. Keep away from heat, sparks and open flames. Use spark-proof tools.
Storage Conditions: Store in tightly sealed containers in a cool, dry, ventilated space away from incompatible substances like oxidizers and acids. Keep container upright to avoid leaks and minimize contact with air.
Incompatible Materials: Oxidizing agents, strong acids, bases, strong reducing agents
General Hygiene: Wash hands after use, remove contaminated clothing and equipment before entering eating areas

Exposure Controls and Personal Protection

Exposure Limits: No OSHA PEL or ACGIH TLV established specifically for 4-vinylphenol, follow good hygiene practices and minimize exposure
Engineering Controls: Use fume hoods, local exhaust ventilation for laboratory work
Respiratory Protection: If ventilation inadequate, wear NIOSH/MSHA-approved organic vapor respirator
Skin Protection: Neoprene, nitrile, or PVC gloves, laboratory coat, long sleeves
Eye Protection: Chemical splash goggles and face shield if risk of splashing
Other Protective Equipment: Use chemical-resistant aprons, maintain eyewash stations and safety showers nearby

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid or crystalline solid
Odor: Weak aromatic odor (phenolic)
Molecular Weight: 120.15 g/mol
Boiling Point: Around 217–219°C
Melting Point: 32°C
Flash Point: 91°C (closed cup)
Autoignition Temp: Not readily available
Vapor Pressure: Low at room temperature
Solubility: Slightly soluble in water, soluble in alcohol and ether
Density: 1.06 g/cm³ at 20°C
pH: Not applicable

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions, risk of polymerization under heat or exposure to light
Hazardous Reactions: May undergo exothermic polymerization with strong acids, bases, or peroxides
Incompatible Materials: Oxidizing agents, strong acids and bases
Decomposition Products: Phenolics, carbon monoxide, carbon dioxide, and other toxic fumes on combustion or thermal breakdown
Conditions to Avoid: Heat, sparks, open flame, sources of static electricity, light exposure

Toxicological Information

Acute Toxicity: Data for 4-vinylphenol specifically limited, phenolic compounds known to cause moderate to high toxicity by ingestion, inhalation, or skin absorption
Skin/Eye Irritation: Causes skin and eye irritation, redness, pain
Carcinogenicity: Not classified by IARC, NTP, or OSHA as carcinogen (data gaps present), phenolic compounds may contain risks
Mutagenicity: No significant data available
Reproductive Toxicity: Some evidence from analogues regarding possible reproductive risk
Target Organs: Skin, eyes, respiratory system
Symptoms of Exposure: Dizziness, headache, nausea, skin/eye redness, coughing, sore throat

Ecological Information

Aquatic Toxicity: Toxic to fish and aquatic organisms, phenolic compounds bioaccumulate and can cause long-term adverse effects
Persistence and Degradability: Phenolic ring slows natural biodegradation, persists in soil and water
Bioaccumulative Potential: May accumulate in aquatic life, disrupts food chains
Mobility in Soil: Moderate, can migrate through soil layers into groundwater
Other Adverse Effects: Harmful to aquatic life with long lasting effects, do not discharge into the environment

Disposal Considerations

Waste Disposal Methods: Incinerate at high temperature in licensed facility, do not release into sewer systems, follow all local and national regulations for hazardous waste
Contaminated Packaging: Rinse thoroughly, dispose as hazardous waste
Precautions: Wear protective gear, avoid spills during handling

Transport Information

UN Number: 3265
UN Proper Shipping Name: Corrosive liquid, acidic, organic, n.o.s. (contains 4-vinylphenol)
Transport Hazard Class: 8 (Corrosive substances)
Packing Group: III
Environmental Hazards: Marine pollutant
Transport Precautions: Keep away from heat or open flames, handle containers upright, use secondary containment

Regulatory Information

Inventory Status: Listed on TSCA, EINECS (European), other global inventories
Hazard Symbols: GHS02 (Flammable), GHS07 (Health hazard), GHS05 (Corrosive)
SARA Title III: Not specifically listed under Section 313, handle by analogy to phenolic substances
Right to Know: States including California, New Jersey, Pennsylvania include phenolic compounds on hazardous substance lists
Other Regulations: Comply with OSHA Hazard Communication Standard, European REACH, and local environmental laws and regulations