Знание
Material Safety Data Sheet (MSDS) – Polyglutamic Acid
Identification
Product Name: Polyglutamic Acid
Synonyms: γ-Polyglutamic Acid, Gamma-PGA
Chemical Formula: (C5H7NO4)n
CAS Number: 25513-46-6
Recommended Use: Water retention agent, moisturizer, biopolymer in cosmetics and medical fields
Supplier: Manufacturer details as per procurement documentation and local distributor contact information
Emergency Phone: Standard emergency response or local poison control center
Hazard Identification
Classification: Product does not fall under hazardous classifications according to OSHA, GHS, or EU standards
Acute Health Effects: May cause slight irritation to eyes and skin in sensitive individuals; no chronic effects known
Environmental Hazards: Not classified as harmful in environmental settings, biodegradable nature noted
Labeling: Not required under standard labeling protocol; good hygiene recommended when handling
Signal Word: None required
Pictograms: None required
Precautionary Statements: Avoid inhalation of dust, contact with eyes, and prolonged contact with skin; wash hands after handling
Composition / Information on Ingredients
Ingredient: Polyglutamic Acid
Concentration: ≥95%
Impurities: Water content (≤5%), low molecular weight polyglutamates, residuals from fermentation (trace)
Additives: None noted; for industrial uses, check if stabilizers or preservatives added on the product batch
First Aid Measures
Eye Contact: Rinse thoroughly under running water for several minutes; remove contacts if present; seek medical attention for persistent irritation
Skin Contact: Wash with soap and lukewarm water; remove contaminated clothing; seek help for allergic reactions
Inhalation: Move the affected person to fresh air; seek attention if symptoms like coughing, shortness of breath, or discomfort develop
Ingestion: Rinse mouth with water; seek medical care if large amounts consumed or symptoms develop
Fire-Fighting Measures
Suitable Extinguishing Media: Water spray, dry chemical, CO2, foam
Unsuitable Extinguishing Media: Direct high-pressure water jets if powder form used, as dust may disperse
Hazardous Combustion Products: Produces carbon oxides, nitrogen oxides, low-molecular organic compounds if burned
Fire Fighter Protection: Wear self-contained breathing apparatus, full protective gear
Special Procedures: Isolate area if large amount involved; keep cooled surrounding containers with water spray
Accidental Release Measures
Personal Precautions: Use gloves, dust mask if powder present, and protective goggles; avoid generating dust
Environmental Precautions: Prevent entry to sewers or waterways
Cleanup Methods: Sweep or vacuum material, collect for disposal; wash spill site with water after removal; for liquid forms, use absorbent materials like sand or vermiculite
Handling and Storage
Safe Handling: Use in well-ventilated areas; avoid prolonged exposure to dust and aerosols; maintain clean workspaces
Conditions for Safe Storage: Store in tightly sealed containers in cool, dry location; protect from sunlight, moisture, and high temperatures
Incompatible Materials: Strong oxidizers, acids, alkaline materials
Storage Group: No special storeroom classification required by law
Exposure Controls and Personal Protection
Engineering Controls: Local ventilation or extraction if dust generated in process
Occupational Exposure Limits: Not established for polyglutamic acid, follow dust exposure standards per OSHA/ACGIH guidelines
Personal Protection: Nitrile gloves, protective lab coat, approved eye protection
Respiratory Protection: Dust mask or NIOSH-certified respirator if highly concentrated powder used
General Hygiene Measures: Do not eat, drink, or smoke in work area; wash hands after use and before meals
Physical and Chemical Properties
Appearance: White to off-white powder, sometimes light yellow granules or clear viscous liquid depending on form
Odor: Slight, characteristic protein or peptide-like
pH: 5 – 8 (for 1% solution in water, varies with degree of polymerization)
Boiling Point: Not applicable (decomposes before boiling, not a volatile compound)
Melting Point: Decomposition at high temperature (above 120°C)
Solubility: Freely soluble in water, insoluble in organic solvents
Relative Density: 1.2 – 1.4 g/cm³
Vapor Pressure: Negligible
Flash Point: Not flammable under typical conditions
Viscosity: Solution form can be highly viscous, depending on concentration and molecular weight
Stability and Reactivity
Chemical Stability: Stable under standard temperatures and pressure
Conditions to Avoid: Extreme heat, direct sunlight, high humidity
Incompatible Materials: Strong acids, strong bases, and oxidizing agents
Hazardous Decomposition: Carbon monoxide, carbon dioxide, nitrogen oxides under fire conditions
Polymerization: Does not undergo dangerous polymerization under recommended usage
Toxicological Information
Routes of Exposure: Skin, eyes, ingestion, inhalation (dust)
Acute Toxicity: Low toxicity based on animal studies; not classified as harmful for acute exposure
Chronic Toxicity: No reports of long-term toxicity; not mutagenic or carcinogenic on available data
Irritation: Mild eye or skin irritation possible for sensitive individuals
Sensitization: No data of significant sensitization in human studies
Other Data: Material used in food and cosmetics at regulated concentrations; oversight in medical uses suggests good safety profile
Ecological Information
Ecotoxicity: No bioaccumulation recorded; not harmful to aquatic or terrestrial life at tested concentrations
Persistence and Degradability: Rapidly biodegradable by microorganisms; breaks down into natural amino acids in soil and water
Mobility in Soil: High water solubility results in tendency to leach; binds weakly to soil particles
Other Adverse Effects: None known; considered environmentally friendly alternative to synthetic polymers
Disposal Considerations
Waste Treatment Methods: Small quantities can be disposed of as regular non-hazardous waste; for large scale, follow local environmental regulations
Disposal of Packaging: Triple-rinse containers and dispose of as non-hazardous material unless otherwise indicated by local rules
Landfill Acceptability: Generally acceptable, but consult local guidelines to confirm
Recycling: No specific methods for recovery; biodegradable nature makes landfill or composting suitable
Transport Information
UN Number: Not assigned, product not considered dangerous for transport
Transport Hazard Class: Non-hazardous material
Packing Group: Not regulated
Marine Pollutant: Not classified as marine pollutant
Special Transport Notes: Protect from rain, keep containers upright, avoid stack collapse in transit
Regulatory Requirements: Shipping based on non-dangerous goods procedures
Regulatory Information
TSCA Status: Listed as a biopolymer not subject to restriction
EINECS/ELINCS: Registered, meets EU chemical safety requirements
OSHA: Considered non-hazardous under US OSHA Hazard Communication Standard
REACH: Registered as non-toxic, non-carcinogenic substance
WHMIS Classification: Not controlled
Additional Local Regulations: Follow additional country or state-specific chemical handling guidance as needed
