Material Safety Data Sheet for Trimethyl Phosphate

Identification

Chemical Name: Trimethyl Phosphate
Synonyms: Phosphoric acid, trimethyl ester; TMP
CAS Number: 512-56-1
Recommended Use: Solvent, flame retardant, intermediate in chemical synthesis
Manufacturer and Supplier Name: [Supplier Information]
Address: [Supplier Address]
Emergency Phone Number: [Supplier Emergency Number]

Hazard Identification

Classification: Flammable liquid, Acute toxicity (oral), Skin and eye irritation, Specific target organ toxicity
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor, harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Pictograms: Flame, exclamation mark, health hazard
Precautionary Statements: Keep away from heat and ignition sources, avoid breathing vapors, wash thoroughly after handling, wear protective gloves, clothing, and eye protection

Composition / Information on Ingredients

Component: Trimethyl Phosphate
Concentration: ≥99%
CAS Number: 512-56-1
Impurities: Trace amounts of methyl phosphates and related esters

First Aid Measures

Inhalation: Move exposed person to fresh air, support breathing if needed, seek immediate medical attention for difficulty breathing or persistent symptoms
Skin Contact: Remove contaminated clothing, immediately flush skin with plenty of water and soap
Eye Contact: Rinse thoroughly with water for at least 15 minutes, seek medical advice if irritation or pain persists
Ingestion: Do not induce vomiting, rinse mouth with water, call poison center or doctor without delay; never give anything by mouth to an unconscious person
Most Important Symptoms: Respiratory irritation, headache, dizziness, digestive discomfort, skin redness, and eye pain

Fire-Fighting Measures

Extinguishing Media: Alcohol-resistant foam, carbon dioxide, dry chemical powder; avoid water jet
Unsuitable Extinguishing Media: Direct water streams may spread the fire
Specific Hazards: Emits toxic fumes under fire conditions, possible formation of phosphoric acids and carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective suits
Special Procedures: Cool fire-exposed containers, control run-off to prevent environmental contamination, evacuate area if excessive vapors or heat

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate, use appropriate personal protective equipment, prevent inhalation of vapors or contact with skin and eyes
Environmental Precautions: Avoid discharge into drains or watercourses, contain spill with non-combustible absorbent material (sand, earth), notify authorities of significant releases
Clean-Up Methods: Absorb spilled material, collect in tightly sealed containers for proper disposal, flush contaminated area with water after material is collected

Handling and Storage

Handling: Handle in a well-ventilated area, keep containers tightly closed, avoid sources of ignition, use explosion-proof equipment, prevent build-up of electrostatic charge
Storage: Store in a dry, cool, well-ventilated place, away from oxidation agents, acids, bases, strong reducing agents, protect from sunlight
Incompatibilities: Acids, strong oxidizers, alkalis
Specific Requirements: Use corrosion-resistant containers, inspect storage areas regularly for leaks or container damage

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA or ACGIH exposure limit; minimize exposure as much as possible
Engineering Controls: Use closed systems, local exhaust ventilation, and chemical fume hoods to minimize vapor release
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or PVC), safety goggles, face shields, impervious clothing, properly fitted respirators in conditions of high vapor concentration
Hygiene Measures: Do not eat, drink, or smoke while handling, wash hands thoroughly after use, remove contaminated clothing before entering clean areas

Physical and Chemical Properties

Appearance: Colorless, clear liquid
Odor: Mild, characteristic
Molecular Formula: C3H9O4P
Molecular Weight: 140.08 g/mol
Melting Point: -46°C
Boiling Point: 197°C
Flash Point: 119°C (closed cup)
Auto-Ignition Temperature: 415°C
Vapor Pressure: 0.4 mmHg (20°C)
Solubility: Soluble in water and organic solvents
Density: 1.186 g/cm³ (20°C)

Stability and Reactivity

Stability: Stable under normal storage and handling conditions
Hazardous Reactions: May react with strong oxidizers, acids, alkalis, generating heat and hazardous fumes
Decomposition Products: Toxic gases including oxides of carbon, phosphoric acid derivatives, and methyl esters
Polymerization: Does not occur
Conditions to Avoid: Heat, flames, sparks, incompatible materials, prolonged exposure to air and moisture

Toxicological Information

Acute Toxicity: Oral LD50 (rat): ~1,600 mg/kg
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Short-Term Effects: Respiratory irritation, nausea, dizziness, eye and skin irritation
Chronic Effects: Prolonged or repeated exposure may damage liver, kidneys, or nervous system
Sensitization: Not classified as a skin sensitizer
Carcinogenicity: No clear evidence of carcinogenic potential based on available animal data

Ecological Information

Ecotoxicity: Harmful to aquatic life, aquatic invertebrates, fish, and algae
Mobility: Readily soluble in water, mobile in soil
Persistence and Degradability: Moderately biodegradable under aerobic conditions
Bioaccumulation Potential: Low tendency for bioaccumulation
Other Adverse Effects: Avoid release to the environment, long-term impact on aquatic systems possible with substantial spills

Disposal Considerations

Waste Disposal: Dispose of contents and container in accordance with local, regional, national, and international regulations
Methods of Disposal: Incineration in certified facility, neutralization by licensed waste service, avoid disposal via drains, watercourses, or landfill
Contaminated Packaging: Triple rinse containers, recycle where possible or dispose as hazardous waste

Transport Information

UN Number: 2328
UN Proper Shipping Name: Trimethyl Phosphate
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: III
Marine Pollutant: Not designated as a marine pollutant
Special Precautions: Ensure proper labeling and secure stowage, consult national transport regulations for additional requirements

Regulatory Information

TSCA Status: Listed
EINECS Number: 208-159-2
SARA Title III Sections: Not rated as extremely hazardous; subject to reporting for determined amounts
OSHA Hazard Communication: Classified as hazardous
WHMIS Classification: Class B2 (Flammable), Class D2B (Toxic/irritant)
Other Regulations: Users must comply with all applicable federal, state, and municipal health and safety regulations